Project LIBRA aims to develop a benchtop multi-sensing system for automated screening of analytes and biomolecules in diverse bioreactors. Differentiated by advanced integration technologies, LIBRA is meant to enable state-ofthe-art integrated photonic devices. These modules are designed to analyze bioreactor samples, providing detailed insights into nutrient compositions and pathogen presence. The device will be able to be adjusted to various bioreactor systems from stirred tank to single use bioreactors (SUB). This project pioneers a new era in bioreactor sample analysis where precision, efficiency, and innovation converge.