Published January 29, 2026 | Version 1.0.0
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ImmunAID-ms-parameters

  • 1. GIGA-institute, CHU Liege, University of Liege
  • 2. ROR icon University of Liège
  • 3. University of Liège - GIGA institute - GIGA proteomics

Description

# ImmunAID-ms-parameters

Normalization parameters used to generate the proteomics data for the paper:

**Adult patients with autoinflammation of unknown origin partially phenocopy the immune presentation of Still’s disease**

## Content of FragPipe parameters folder
 
This repository includes two key configuration files for the FragPipe/MSFragger pipeline.

- The `fragger.params` file defines all database search settings (e.g. enzyme specificity, mass tolerances, allowed missed cleavages, and fixed/variable modifications), ensuring the MS/MS search is fully reproducible and its search space is clearly documented.

- The `sdrf.tsv` file follows the Sample and Data Relationship Format and describes the experimental design and sample metadata for each LC-MS/MS run (such as biological conditions, replicates, and raw file paths), enabling correct sample grouping, downstream statistical analysis, and transparent linkage between raw data and biological context.
 
## How to cite:
If you use these parameters, please cite it as follows:

Poulet, C., & Baiwir, D. (2026). ImmunAID-ms-parameters (Version 1.0.0) [Dataset]. University of Liège - GIGA Institute. Zenodo. https://doi.org/10.5281/zenodo.18413673
License: CC BY-NC-ND 4.0
Repository: https://gitlab.uliege.be/giga-rheumatology/public/immunaid-ms-parameters

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Additional details

Funding

European Commission
ImmunAID - Immunome project consortium for AutoInflammatory Disorders 779295