This policy brief is D1.3 (T1.2) of the Horizon Europe project GS4S - Global Strategy for Skills, Migration and Development (gs4s.eu). The brief was prepared by coordinators of the project to engage with the policy dialogue and respond to the search for precise, comprehensive, effective, and sustainable solutions for skills shortages in Digital, Care and Construction sectors. Halfway into the GS4S project, we draw on interim interdisciplinary evidence and go straight to 20 policy recommendations in areas of migration, education, development, and trade (or, as the project coins it, “MEDT” policies). Building on this structure, we emphasize solutions to skills shortages lie at the intersection of MEDT policies. Our key recommendations highlight the need to (i) expand and improve legal migration pathways to attract and retain talent (ii) invest in skills development and facilitate procedures for recognition of qualifications, (iii) revisit the design, objectives and evaluation of EU Talent Partnerships and (iv) address persistent challenges with data availability. The policy brief is primarily addressed at the European Commission (DG EMPL, DG HOME, DG TRADE, DG ENEST, DG ECFIN, DG GROW). However, it is also informative for other audiences: policymakers on the EU, national- and local-levels, scholars, researchers, representatives of civil society organizations, social partners, and industrial associations.