Fishmeal is recognised as a premium protein source in aquaculture diets. However, the high
reliance on it, as the main protein source in aquafeeds, has led to over-exploitation of marine
resources, resulting in sustainability and economic issues. Efforts to reduce unsustainable
catches have resulted in a reduced supply of marine ingredients for aquafeed production. In
addition, several plant ingredients have been investigated as alternatives to fishmeal, with
controversial results. A new potential source that does not compete with human food supplies
and has no economic value, are invasive species such as Lagocephalus sceleratus (Gmelin,
1789). These have rapidly established themselves in the Eastern Mediterranean, with various
impacts on the ecosystem and human welfare, and may provide an alternative marine protein
source to conventional fishmeal. The aim of the current study was to evaluate in vitro the
fishmeal produced by Lagocephalus sceleratus compared to conventional fishmeal.