This deliverable D6.1 – “General overview of inline/online NanoPAT solutions in different industrial processes” is developed as part of the NanoPAT project, which is a European Union Horizon 2020 Research and Innovation Program, under the Grant Agreement number 862583.
It has been produced by the University of Potsdam, as leader of WP6, with the collaboration of POLYMAT / UPV, FLUIDINOVA, Arkema, Analisis-DSC, Evonik, Medical University Graz, BRAVE Analytics GmbH, ZHAW and Creative Nano.

It contains as its title already introduces, a general overview of the inline/online solutions provided by the NanoPAT project for different industrial processes, concretely for polymeric dispersions, nanostructured synthetic amorphous silica (SAS) particles, hydroxyapatite nanoparticles, zeolite nanoparticles, and ceramic nanoparticles.

The demand for nanoscale materials and nanoparticles in industry has been increasing rapidly in recent years. Novel process analytical technologies (PATs) have the potential to increase the production rate of nanomaterials, control their product quality, enhance product safety, and save valuable energy, material, and time resources.

The NanoPAT project is focused on advancing three complementary real-time particle characterization PATs - Photon Density Wave spectroscopy (PDW), OptoFluidic Force induction (OF2i), and Turbidity spectrometry (TUS) - from the "lab-status" (TRL 4) to a technology demonstration level at pilot scale in an industrial environment (TRL 6). This will provide, for the first time, real-time analysis for manufacturing processes of particles in the nanometer scale with sub-minute temporal resolution.

To achieve this aim, five industrially relevant cases have been selected: Polymer dispersion, silica, hydroxyapatite, zeolite, and ceramic case studies. Over the past 18 months, our research and technology organizations have evaluated and optimized the three PATs for these specific case studies. Currently, the processes are being scaled-up to be implemented at the pilot plants of our industrial partners, Covestro, Evonik, FLUIDINOVA, Arkema, and Cnano. The following report provides an overview of the NanoPAT solutions in the five industrial processes.