Published June 27, 2023 | Version v1
Project deliverable Open

SIMCor. Deliverable 6.5 - Specification and quantification of synthetic boundary conditions (CHA, M30)

  • 1. Charité Universitätsmedizin Berlin
  • 2. Charité - Universitätsmedizin Berlin


This document provides specifications for the generation of synthetic boundary conditions. Synthetic boundary conditions are required in two instances. First, they can be used to describe virtual patients or datasets to be analysed via in-silico modelling. Second, they can be used to replace or impute missing information for in-silico assessment of real animal- or patient-specific cases. At first, a generic consideration regarding standardisation, relevant quality measures, and file formats is provided. Subsequently, the relevant synthetic boundary conditions for both project use cases, i.e., transcatheter aortic valve implantation (TAVI) and pulmonary artery pressure sensor (PAPS), are provided. The detailed descriptions of the use cases and data elements are used as dedicated examples for the more generic considerations. Here, the focus will lie on the generation of synthetic surface geometries, i.e., the anatomical boundary conditions, as the generation of functional boundary conditions, such as volume flow rates, was already addressed in D6.4 - Specification and quantification of subject-specific data-based boundary conditions (CHA, M24), both for patient-specific and synthetic cases.

SIMCor (In-Silico testing and validation of Cardiovascular IMplantable devices) has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 101017578.



Additional details


SIMCOR – In Silico testing and validation of Cardiovascular Implantable devices 101017578
European Commission