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ANGIE - MAgnetically steerable wireless Nanodevices for the tarGeted delivery of therapeutIc agents in any vascular rEgion of the body

ANGIE - MAgnetically steerable wireless Nanodevices for the tarGeted delivery of therapeutIc agents in any vascular rEgion of the body

This repository community collects research outputs related to the ANGIE project. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 952152”

MAgnetically steerable wireless Nanodevices for the tarGeted delivery of therapeutIc agents in any vascular rEgion of the body – ANGIE - aims to develop a novel, minimally invasive approach for treatment of strokes.
Most strokes occur when a blood vessel in the brain is occluded by a clot. This clot then prevents areas in the brain from being supplied with oxygen, resulting in the sudden death of brain tissue. Strokes are a leading cause of death and disability worldwide, and stroke cases are expected to rise in the coming years. The most common treatment for this kind of stroke involves injecting a thrombolytic drug (usually rtPA) into the blood, which then dissolves the clot. Tiny mobile magnetic devices are showing huge potential for future biomedical applications. The EU-funded ANGIE project will forge ahead with small-scale robotics, magnetic navigation systems and localised targeted drug delivery. Specifically, the project will develop magnetically steerable wireless nanodevices for the targeted delivery of therapeutic agents via the body's vascular system. By creating a baseline of knowledge and skills for localised targeted drug delivery, the project will increase health professionals' capacity to treat multiple chronic diseases. Moreover, it will enable doctors to deliver drugs precisely where needed with minimal side effects.