Published December 13, 2022 | Version v3
Journal article Open

supplementary data Designing and Evaluation of Ebastine –Benzamide Cocrystals

  • 1. 1Department of Pharmaceutics College of Pharmacy, University of Baghdad, Baghdad, Iraq

Description

grinding.xlsx
slurry.xlsx
smilarity test for differant method.xlsx
solvent evapo.xlsx
all these above files are (invitro dissolution profile similarity tests)

all formula 2.spv -contain Solubility analysis by spss of All formula 
benzamid formula.sav Solubility analysis by spss of benzamide formula
the supplemantry (2).docx contain the following 

 

 

Fig (1) Ebastine  chemical imaging by raman spectroscopy

Fig (2) benzamide  chemical imaging by raman spectroscopy

Fig (3) Ebastine- Benzanide (1_8) molar ratiophysical mixture  chemical imaging by raman spectroscopy

Fig (4) Ebastine- Benzanide (1_8) molar ratio cocrystal  chemical imaging by raman spectroscopy

Fig (5) SEM of ebastine

Fig (5) SEM of benzamide

Fig (6) SEM of Ebastine- Benzanide (1_8) molar ratio cocrystal 

Fig (7) ebastine structure by Avogadro  software

Fig (8)  BENE structure by Avogadro software

Fig (9) EB-BENZ cocrystal (1-8) molar ratio

Fig(10) release profile of cocrystal in EB-BENZ  (1-4) molar ratio in a different method

Fig(11) release profile of cocrystal in EB-BENZ  (1-8) molar ratio in a different method

fig(12) optical microscope (a)EB(b) BENZ(c)EB-BENZ3(SE)(d)EB- BENZ6slurry(e) EB-BENZ9(LAG)

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