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Published November 28, 2023 | Version v1
Dataset Open

Systematic lineage mapping uncovers polyclonal-to-monoclonal preneoplastic evolution

Creators

  • 1. CAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China
  • 2. SIAT-HKUST Joint Laboratory of Cell Evolution and Digital Health, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China
  • 3. Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau, China
  • 4. MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China
  • 5. School of Mathematical Sciences, Xiamen University, Xiamen, China
  • 6. National Institute for Data Science in Health and Medicine, Xiamen University, Xiamen, China
  • 7. Ministry of Education Frontiers Science Center for Precision Oncology, University of Macau, Macau, China
  • 8. Department of General Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
  • 9. Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
  • 10. Department of Chemical and Biological Engineering, Division of Life Science, State Key Laboratory of Molecular Neuroscience, Hong Kong University of Science and Technology, Hong Kong SAR, China
  • 11. Hong Kong Center for Neurodegenerative Diseases, InnoHK, Hong Kong SAR, China
  • 12. Key Laboratory of Human Microbiome and Chronic Diseases (Sun Yat-sen University), Ministry of Education, Guangzhou, China

Description

Data and code for Systematic lineage mapping uncovers polyclonal-to-monoclonal preneoplastic evolution: 

This dataset contains reproducibility, pipeline and data for 4 parts of the paper, including PacBio data analysis, scRNA-seq data analysis, HumanCRC data analysis and WGS data analysis. 

See readme.txt in each folder for more details. 

Files

data_and_scripts.zip

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