Published June 14, 2024
| Version v2
Dataset
Open
Systematic lineage tracing unveils polyclonal origin and evolution in colorectal precancer
Creators
- Lu, Zhaolian1, 2
- Mo, Shanlan1, 2
- Xie, Duo1, 3
- Zhai, Xiangwei4
- Deng, Shanjun4
- Zhou, Kantian1
- Wang, Kun1, 5, 6
- Kang, Xueling1
- Zhang, Hao1, 2
- Tong, Juanzhen1, 2
- Hou, Liangzhen1, 3
- Hu, Huijuan1
- Li, Xuefei1
- Zhou, Da5, 6
- Lee, Leo Tsz On3, 7
- Liu, Li4
- Zhu, Yaxi8
- Yu, Jing9, 10
- Lan, Ping9, 10
- Wang, Jiguang11, 12
- He, Zhen9, 13
- He, Xionglei4
- Hu, Zheng1, 2
- 1. Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China
- 2. SIAT-HKUST Joint Laboratory of Cell Evolution and Digital Health, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China
- 3. Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau, China
- 4. MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China
- 5. School of Mathematical Sciences, Xiamen University, Xiamen, China
- 6. National Institute for Data Science in Health and Medicine, Xiamen University, Xiamen, China
- 7. Ministry of Education Frontiers Science Center for Precision Oncology, University of Macau, Macau, China
- 8. Department of Pathology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
- 9. Department of General Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
- 10. Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
- 11. Department of Chemical and Biological Engineering, Division of Life Science, State Key Laboratory of Molecular Neuroscience, Hong Kong University of Science and Technology, Hong Kong SAR, China
- 12. Hong Kong Center for Neurodegenerative Diseases, InnoHK, Hong Kong SAR, China
- 13. Key Laboratory of Human Microbiome and Chronic Diseases (Sun Yat-sen University), Ministry of Education, Guangzhou, China
Description
Data and code for Systematic lineage tracing unveils polyclonal origin and evolution in colorectal precancer:
This dataset contains reproducibility, pipeline and data for 4 parts of the paper, including PacBio data analysis, scRNA-seq data analysis, HumanCRC data analysis and WGS data analysis.
See readme.txt in each folder for more details.
Files
data_scripts.zip
Files
(1.2 GB)
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md5:48f301f31095a5aa76dea6341f473d7b
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