Depression - the first symptom of a brain tumor or a consequence of the process neoplastic process - a review of the literature

ANTKOWIAK, Klaudia, CIECIERSKI-KOŹLAREK , Hubert, ŻUREK, Urszula, TOŁWIŃSKI, Ignacy, KĘDZIERSKA, Zofia, DADAS, Klaudia, ŚWIERCZ, Aleksandra, MAŁACHOWSKA, Dominika and SHVED, Kateryna. Depression - the first symptom of a brain tumor or a consequence of the process neoplastic process - a review of the literature. Journal of Education, Health and Sport. 2023;46(1):233-246. eISSN 2391-8306. https://dx.doi.org/10.12775/JEHS.2023.46.01.016

https://apcz.umk.pl/JEHS/article/view/45338

https://zenodo.org/record/8284926

The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of 17.07.2023 No. 32318. Has a Journal's Unique Identifier: 201159. Scientific disciplines assigned: Physical Culture Sciences (Field of Medical sciences and health sciences); Health Sciences (Field of Medical Sciences and Health Sciences).

Punkty Ministerialne z 2019 - aktualny rok 40 punktów. Załącznik do komunikatu Ministra Edukacji i Nauki z dnia 17.07.2023 Lp. 32318. Posiada Unikatowy Identyfikator Czasopisma: 201159.

Przypisane dyscypliny naukowe: Nauki o kulturze fizycznej (Dziedzina nauk medycznych i nauk o zdrowiu); Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu).

© The Authors 2023;

This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland

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The authors declare that there is no conflict of interests regarding the publication of this paper.

Received: 25.07.2023. Revised:21.08.2023. Accepted: 25.08.2023. Published: 29.08.2023.

Depression- the first symptom of a brain tumor or a consequence of the process  neoplastic process - a review of the literature

Klaudia Antkowiak                                                                                                                        Szpital Średzki Serca Jezusowego z.o.o ul. Żwirki i Wigury 10, 63-000 Środa Wielkopolska, Poland                                                                                                                                                 ORCiD: 0009-0008-3421-2200                                                                                                                       e-mail: klaudia.antkowiak2021@gmail.com

Hubert Ciecierski-Koźlarek                                                                                                        Wojewódzki Szpital Specjalistyczny w Olsztynie, ul. Żołnierska 18, 10-561 Olsztyn, Poland                           ORCiD: 0009-0009-4062-6888                                                                                                                       e-mail: hubertciecierski@icloud.com

Urszula Żurek                                                                                                                                       Warszawski Szpital Południowy, ul. rtm. Witolda Pileckiego 99, 02-781 Warszawa, Poland      ORCiD: 0009-0008-3482-5381                                                                                                                e-mail: ula.zurek@gmail.com

Ignacy Tołwiński                                                                                                                       Warszawski Szpital Południowy, ul. rtm. Witolda Pileckiego 99, 02-781 Warszawa, Poland                             ORCiD: 0000-0003-1362-6734                                                                                                            e-mail: ignacyt233@gmail.com

Zofia Kędzierska                                                                                                                         Warszawski Szpital Południowy, ul. rtm. Witolda Pileckiego 99, 02-781 Warszawa, Poland ORCiD: 0000-0002-4181-4719                                                                                                                   e-mail: zo.kedzierska@gmail.com 124

Klaudia Dadas                                                                                                                          Warszawski Szpital Południowy, ul. rtm. Witolda Pileckiego 99, 02-781 Warszawa, Poland ORCiD: 0009-0007-3352-9807                                                                                                                      e-mail: klaudia.w.2703@gmail.com

Aleksandra Świercz                                                                                                                      Warszawski Szpital Południowy, ul. rtm. Witolda Pileckiego 99, 02-781 Warszawa, Poland ORCiD: 0009-0007-1535-1590                                                                                                                  e-mail: aleksandra.swiercz1996@gmail.com

Dominika Małachowska                                                                                                          Warszawski Szpital Południowy, ul. rtm. Witolda Pileckiego 99, 02-781 Warszawa, Poland ORCiD: 0009-0008-6305-7959                                                                                                                e-mail: dominika1.malachowska@gmail.com

Kateryna Shved                                                                                                        Wielospecjalistyczny Szpital Miejski im. Józefa Strusia, ul. Szwajcarska 3, 61-285 Poznań, Poland                                                                                                                                              ORCiD: 0009-0002-3773-7025                                                                                                                 e-mail: katey.shved@gmail.com

Abstract:

Introduction and objective

CNS malignancies account for about 1.6% of all diseases today. In people diagnosed with a
brain tumor with a poor prognosis, we often see disorders from the psychiatric spectrum,
most often depressive disorders. In this paper, we want to focus on whether depression occurs
as a sequel to cancer or perhaps is the first of the symptoms of a CNS tumor.

Review methods

For the analysis, the PubMed medical database was searched, and articles containing studies
and case reports of people with CNS tumor and depressive disorders that occurred either
before diagnosis or at any time during the course of the disease were selected

Abbreviated description of the state of knowledge

CNS tumors produce symptoms such as epilepsy, visual disturbances, paresis, but also
behavioral disorders. This is determined by the location of the tumor. Depression is a mental
disorder manifested mainly by lowered mood. This disorder can coexist with tumors
occurring in the frontal lobe or be present regardless of the location of the tumor, in people
diagnosed with a tumor with a poor prognosis.

Summary

Analyzing the selected articles, we see that in people who were diagnosed with a tumor
located in the frontal lobe, often the first symptom was depressive disorders, which even
preceded neurological symptoms. When depression is diagnosed, appearing suddenly and
refractory to treatment, one should consider whether there is an underlying pathological
lesion in the CNS. Unfortunately, there are no specific guidelines for imaging studies in
depressive disorders. People who suffer from malignant tumors with a poor prognosis should
be cared for by a psychologist, because as the disease progresses, the symptoms worsen,
affecting the prognosis.

Keywords: brain tumor; glioblastoma multiforme; depression; cognitive impairment; cancer.