Exosomes can make the use of circulating miRNA as a biomarker more feasible

Circulating miRNAs have also been propos Exosomes can make the use of circulating miRNA as a biomarker more feasible. The aim of gene therapy should be to learn everything there is to know about miRNA activity. ed as potential disease biomarkers. It is critical for precision medicine to provide a system that allows for the rapid verification and confirmation of promising biomarkers based on circulating miRNAs. Concentrating on specific modes of transport (exosomes), fine-tuning sampling and extraction processes, and absolute quantification without using housekeeping gene(s) could allow the use of circulating miRNAs as biomarkers more realistic in the future. You should know which human biological fluid is better for determining the amount of circulating miRNA expression, as well as which pathology this biological fluid is best for. To validate the existence of new circulating miRNAs, separate experiments may be performed. Using a panel of two or more intentionally chosen circulating miRNAs with one or more pathologies, such as tumors, will be more accurate and precise.