Evaluation of quantitative-qualitative levels of blood pressure by Tensioregulome

KOZYAVKINA, Nataliya, POPOVYCH, Igor, VOVCHYNA, Yuliya, VORONYCH-SEMCHENKO, Nataliya, ZUKOW, Walery & POPOVYCH, Dariya. Evaluation of quantitative-qualitative levels of blood pressure by Tensioregulome. Journal of Education, Health and Sport. 2022;12(8):1216-1236. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2022.12.08.106

https://apcz.umk.pl/JEHS/article/view/44305

https://zenodo.org/record/7988796

The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of December 21, 2021. No. 32343.

Has a Journal's Unique Identifier: 201159. Scientific disciplines assigned: Physical Culture Sciences (Field of Medical sciences and health sciences); Health Sciences (Field of Medical Sciences and Health Sciences).

Punkty Ministerialne z 2019 - aktualny rok 40 punktów. Załącznik do komunikatu Ministra Edukacji i Nauki z dnia 21 grudnia 2021 r. Lp. 32343. Posiada Unikatowy Identyfikator Czasopisma: 201159.

Przypisane dyscypliny naukowe: Nauki o kulturze fizycznej (Dziedzina nauk medycznych i nauk o zdrowiu); Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu).

© The Authors 2022;

This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland

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The authors declare that there is no conflict of interests regarding the publication of this paper.

Received: 02.07.2022. Revised: 07.08.2022. Accepted: 26.08.2022.

Evaluation of quantitative-qualitative levels of blood pressure by Tensioregulome

Nataliya V. Kozyavkina^1,4, Igor L. Popovych^1,5,6, Yuliya V. Vovchyna², Nataliya M. Voronych-Semchenko², Walery Zukow³, Dariya V. Popovych⁴

¹Kozyavkin International Rehabilitation Clinic, Truskavets’, Ukraine

nataliakozyavkina72@gmail.com; center@reha.lviv.ua

²Ivano-Frankivs’k National Medical University, Ivano-Frankivs’k, Ukraine

³Nicolaus Copernicus University, Torun, Poland   w.zukow@wp.pl

⁴IY Horbachevs’kyi National Medical University, Ternopil’, Ukraine  darakoz@yahoo.com

⁵Ukrainian Scientific Research Institute of Medicine of Transport, Odesa

⁶OO Bohomolets’ Institute of Physiology, Kyїv   i.popovych@biph.kiev.ua

Abstract

Background. Earlier we showed that the qualitative-quantitative clusters of blood pressure (BP) are very clearly different from each other by age, sex and the constellation of neuro-endocrine, immune and metabolic variables, which we called the Tensioregulome by analogy with the metabolome and the microbiome. The purpose of this study is detailing this concept. Materials and methods. Under an observations were 44 patients with chronic pyelonephritis and cholecystitis in the phase of remission. Testing was performed twice - on admission and after 7-10 days of standard balneotherapy. The main object of the study was BP. We determined parameters of EEG and HRV, plasma levels of adaptation hormones, electrolytes, lipids, and nitrogenous metabolites, components of humoral, cellular, and phagocytic links of immunity and microbiota as well as markers of pyelonephritis. Results. The forward stepwise program identified 42 Tensioregulome parameters as characteristic of quantitative-qualitative blood pressure clusters: 25 EEGs, sympathetic tone, cortisol, calcitonin, Bifidobacteria faeces, 5 metabolic and 5 immune parameters as well as sex and age. The accuracy of patient classification is 97,7%. Another 15 parameters were found to be characteristic, but were outside the discriminant model. Non-linear correlations between the BP and Tensioregulome parameters were revealed. Conclusion. The Tensioregulome allows us to reliably evaluate quantitative-qualitative levels of blood pressure without measuring it with a tonometer.

Keywords: blood pressure, EEG, HRV, hormones, immunity, metabolome, pyelonephritis.