Published November 3, 2021 | Version v1
Journal article Open

Basal expression of RAD51 foci predicts olaparib response in patient-derived ovarian cancer xenografts

  • 1. Laboratory of Molecular Pharmacology, Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy
  • 2. Laboratory of Methodology for Clinical Research, Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
  • 3. Laboratory of Cancer Metastasis Therapeutics, Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
  • 4. Laboratory of Molecular Pharmacology, Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
  • 5. Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology, Barcelona, Spain
  • 6. Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology, Barcelona, Spain.
  • 7. Clinic of Obstetrics and Gynecology, Department of Medicine and Surgery, San Gerardo Hospital, University of Milan Bicocca, Monza, Italy.
  • 8. MRC Cancer Unit, Hutchison/MRC Research Centre, University of Cambridge, Box 197, Cambridge Biomedical Campus, Cambridge, CB2 0XZ, UK. - Academic Laboratory of Medical Genetics, Lv 6 Addenbrooke's Treatment Centre, Addenbrooke's Hospital, Box 238, Cambridge, CB2 0QQ, UK.
  • 9. Laboratory of Cancer Metastasis Therapeutics, Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy
  • 10. Unit of Gynecological Oncology Research, European Institute of Oncology, Milan, Italy.
  • 11. Laboratory of Molecular Pharmacology, Department of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy. giovanna.damia@marionegri.it.

Description

Caratterizzazione farmacologica dei modelli xenograft derivanti da pazienti con carcinoma ovarico utilizzati per esperimenti pubblicati.

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3473-2853 (ISSN)