FORMULATION AND EVALUATION OF HERACLEUM CANDOLLEANUM GRANULES FOR DETERMINATION OF ANTIOXIDANT ACTIVITY

This research work includes formulation and evaluation of herbal granules of Heracleum candolleanum Gamble along with determination of antioxidant activity. It is essential to determine its medicinal values for the development of herbal alternative to synthetic drugs. It is commonly called as Chittelam seeds which are native to Europe, Asia and widely found in Kerala. Successive Soxhlet extraction process used to extract the content. Presence of alkaloids, flavonoids, glycosides, terpenoids and volatile oils confirmed after phytochemical evaluation. Antioxidant activity of extracts were determined by using DPPH scavenging assay. Dried extract with antioxidant activity formulated into granules which poses excellent flow properties.

Keywords: Chittelam seeds, Soxhlet extraction, Antioxidant activity, Herbal Granules.