Current prospects of urine cytology in diagnosis and follow-up urinary tract malignancies - the short review

Jarosz Piotr M., Oszczędłowski Paweł, Pytka Michalina, Nowaczek Justyna, Jodłowska-Jędrych Barbara. Current prospects of urine cytology in diagnosis and follow-up urinary tract malignancies - the short review. Journal of Education, Health and Sport. 2020;10(9):763-769. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2020.10.09.092

https://apcz.umk.pl/czasopisma/index.php/JEHS/article/view/JEHS.2020.10.09.092

https://zenodo.org/record/4051874

The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019.

© The Authors 2020;

This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland

Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike.

(http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.

The authors declare that there is no conflict of interests regarding the publication of this paper.

Received: 22.09.2020. Revised: 24.09.2020. Accepted: 26.09.2020.

Current prospects of urine cytology in diagnosis and follow-up urinary tract malignancies - the short review

Piotr M. Jarosz¹, Paweł Oszczędłowski¹, Michalina Pytka¹, Justyna Nowaczek¹,

Barbara Jodłowska-Jędrych¹

¹ Chair and Department of Histology and Embryology with Experimental Cytology Unit, Medical University of Lublin, Radziwiłłowska Street 11, 20-080 Lublin, Poland

Piotr M. Jarosz; pjarosz196@gmail.com; ORCID: 0000-0003-0489-2600;
Paweł Oszczędłowski; pawelosz99@gmail.com; ORCID 0000-0001-7406-550X;
Michalina Pytka; michalinapytka@gmail.com; ORCID: 0000-0002-4813-9357;
Justyna Nowaczek; justynafaustynanowaczek@gmail.com; ORCID: 0000-0001-7622-2345;
Barbara Jodłowska-Jędrych; barbara.jodlowska-jedrych@umlub.pl;
ORCID: 0000-0003-3483-8752

Summary:

Introduction and purpose: Cytology of urine sediment is a diagnostic tool used to screen for urinary tract lesions in two cases: surveillance of patients with a history of urothelial malignancies and patients with unexplained, new onset haematuria. Since 2015 histopathological laboratories have been able to report urine cytology according to The Paris System (TPS).  Current studies suggest usefulness of urinary cytology in follow-up of urinary tract malignancies, especially urinary bladder cancer, which is the 13^th most deadly throughout the world being responsible for 200 000 deaths in 2018 among neoplasms.

Objective: To review currently available data on PubMed about usefulness urine cytology reporting in follow-up and diagnosis of urinary tract malignancies.

A brief description of the state of knowledge: Advantages of urine cytology examination contain non-invasiveness, high specificity, lower cost than cystoscopy and enable immunohistochemistry performance as well. Implementation of The Paris System for reporting urine cytology has created an universally acceptable and globally used report system. Reporting according to TPS significantly reduced the number of cases described as atypical changes.

Conclusions: Urinary cytology is used to supplement endoscopic evaluation of the urinary tract in the screening and the surveillance of urothelial carcinoma. The Paris System for reporting urinary cytology has clarified the diagnostic categories of urine sediment examination. Cystoscopy and urine cytology are the standard tools for monitoring urinary tract malignancies.

Key words: urinary tract; urinary bladder cancer; urine cytology; The Paris System; immunohistochemistry