BK Channels activation by N-type Ca2+ channels in the dendrites of neocortical pyramidal neurons
Description
This dataset contains imaging and whole-cell electrophysiological recordings from neocortical layer-5 pyramidal neuron dendrites in brain slices of the mouse.
Somatic electrophysiological and dendritic imaging recordings were done at 20 kHz. Imaging recordings were done with ~2.5 µm nm pixel resolution. These correspond to:
- Voltage imaging (Figures 1 and 7)
- Calcium imaging (Figures 2,3 and 4).
This dataset is used in the paper:
Blömer LA, Giacalone E, Abbas F, Filipis L, Migliore M, Canepari M. Kinetics and functional consequences of BK Channels activation by N-type Ca2+ channels in the dendrite of mouse neocortical layer-5 pyramidal neurons. bioRxiv, 2023 (https://www.biorxiv.org/content/10.1101/2023.10.26.564136v1).
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Additional details
Funding
- OptChemCom – Integrated optical, photochemical and computational technologies to study the physiological synergy of different ion channels ANR-18-CE19-0024
- Agence Nationale de la Recherche
- ICST – Canaux ioniques d'intérêt thérapeutique ANR-11-LABX-0015
- Agence Nationale de la Recherche