The Penn State SETI Symposium was held in State College, PA June 27-30, 2022. We take ecumenical view of SETI as the astronomical search for technosignatures, and as a subfield of astrobiology. It encompassed technosignatures across and beyond the electromagnetic spectrum, including (but not limited to) radio, microwave, optical, and NIR signals compressed in the time and frequency domains; multimessenger astronomy; megastructures in transit and thermal emission; and solar system SETI.