The One Health European Joint Program (OHEJP) aims at integrating the complementary expertise of partners across Europe in order to prepare common action against infectious health threats. Those threats include zoonotic infections both in animals and humans, and infections or toxin contamination in feed and food. To reach the objective, the OHEJP consortium will develop a sustainable framework for an integrated community of research groups. Research groups are represented by reference laboratories in fields of human and veterinary medicine, food and environmental sciences. The OHEJP will emphasis on food-borne microbial infections and intoxications, in the scope of a One Health perspective.