Sars-Cov-2 and Mers sequences from human host with no unknown characters

Description

Methods

Raw datasets are genome sequences retrieved from the National Center for Biotechnology Information (NCBI) database (https://www.ncbi.nlm.nih.gov). The sequences were filtered according to the following criteria:

1) Sars-Cov-2 dataset. This dataset contains complete genome sequences from a human host, with none unknown characters.  In the NCBI database, there are about 950.000 sequences with these characteristics.

2) Restricted Sars-Cov-2 dataset: This dataset contains complete genome sequences from a human host, with no unknown characters, with 29903 bases, that is of the same length as the reference sequence NC045512.2. We obtained, from the NCBI database, about 5600 sequences with such features.

3) Mers dataset: We selected about 200 complete genome sequences from a human host, with no unknown characters.

Raw data have been processed through a C++ code (provided with the datsets) that reads a dataset of nucleic acid sequences in FASTA format and returns the number of bases in each sequence. The output file seqcount.txt contains a table organized as follows: first column, number of bases in a given sequence; second, third, fourth and fifth columns, number of bases of type A, C, G and T, respectively, in the same sequence. Each row reports the data calculated for successive sequences following the same order of the raw datasets.