Published September 19, 2023
| Version v0.4.1
Software
Open
USDA-ARS-GBRU/GuideMaker: v0.4.1
Description
- Changed how Guidemaker handles DNA sequences that are soft-masked with lowercase letters. The new behavior unmasks all sequences and finds guide candidates (and filters them for distance) against the entire sequence. It also fixes a key value error in computing the Doench efficiency scores when mixed case sequences were used. Previously, guides were only identified in regions where the PAM was all capitalized and edit distance was different if the case was different (a capitalized and lowercase guide were not considered the same).
- Dockerfiles now have more version information
- GitHub build actions were improved
Files
USDA-ARS-GBRU/GuideMaker-v0.4.1.zip
Files
(6.8 MB)
| Name | Size | Download all |
|---|---|---|
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md5:bd97c4fa54cd62f472d7bc66305300fd
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6.8 MB | Preview Download |
Additional details
Related works
- Is supplement to
- https://github.com/USDA-ARS-GBRU/GuideMaker/tree/v0.4.1 (URL)