Published September 12, 2023 | Version 6.3
Preprint Open

Preprint: "Be Sustainable", Recommendations for FAIR Resources in Life Sciences research: EOSC-Life's Lessons

  • 1. European Research Infrastructure on Highly Pathogenic Agents (ERINHA)
  • 2. Euro-BioImaging ERIC Bio-Hub, European Molecular Biology Laboratory (EMBL)
  • 3. University of Dundee
  • 4. European Molecular Biology Laboratory
  • 5. Instruct-ERIC
  • 6. European Advanced Translational Research Infrastructure (EATRIS)/Lygature
  • 7. VIB Data Core
  • 8. BBMRI-ERIC, Biobanking and BioMolecular Resources Research Infrastructure (BBMRI-ERIC)
  • 9. Flanders Marine Institute
  • 10. IBG-2: Plant Sciences
  • 11. Istituto di Ricerche Farmacologiche Mario Negri IRCCS
  • 12. The University of Manchester
  • 14. TU Wien, Research Unit Data Science
  • 15. Albert-Ludwigs-Universitat Freiburg
  • 16. European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory
  • 17. University of Ljubljana
  • 18. BBMRI-ERIC Biobanking and BioMolecular Resources Research Infrastructure (BBMRI-ERIC)
  • 19. Dept of Computer Science, The University of Manchester
  • 20. Investigative Science Team, Historic England
  • 21. Universitat Pompeu Fabra, Department of Humanities, CASEs Research Group and ICREA
  • 22. Universite de Montpellier, INRAE, Institut Agro Montpellier
  • 23. Oxford e-Research Centre, Department of Engineering Science, University of Oxford
  • 24. Istituto di Biostrutture e Bioimmagini, Consiglio Nazionale delle Ricerche
  • 25. EATRIS ERIC, European Infrastructure for Translational Medicine
  • 26. Escuela Superior de Ingenieros, Universidad de Sevilla/AICIA- Asoc.Invest.Coop.Ind.Andalucia
  • 27. Istituto di Biochimica e Biologia Cellulare, Consiglio Nazionale delle Ricerche (CNR)
  • 28. The Alan Turing Institute, British Library
  • 29. Biobanking and Biomolecular Resources Research Infrastructure (BBMRI-ERIC)
  • 30. European Clinical Research Infrastructure Network (ECRIN)
  • 31. INSERM
  • 33. IRCCS Ospedale Policlinico San Martino
  • 34. Department of Chemistry and Magnetic Resonance Center, University of Florence
  • 35. Vall d'Hebron Institut de Recerca, Universitat de Barcelona
  • 36. University of Helsinki
  • 37. Institute for Molecular Medicine Finland, University of Helsinki
  • 38. ELIXIR Hub
  • 39. Group Leader Cloud and HPX, Center for Digital Health, BIH@Charite University Medicine
  • 40. University of Amsterdam, Free University Amsterdam, University of Manchester
  • 41. ITMP Head Discovery Research (ITMP Drug Discovery)


"Be SURE - Be SUstainable REcommendations"

The main goals and challenges for the Life Science (LS) communities in the Open Science framework are to increase reuse and sustainability of data resources, software tools, and workflows, especially in large-scale data-driven research and computational analyses. Here, we present key findings, procedures, effective measures and recommendations for generating and establishing sustainable LS resources based on the collaborative, cross-disciplinary work done within the EOSC-Life (European Open Science Cloud for Life Sciences) consortium. Bringing together 13 European LS Research Infrastructures (RIs), it has laid the foundation for an open, digital space to support biological and medical research. Using lessons learned from 27 selected projects, we describe the organisational, technical, financial and legal/ethical challenges that represent the main barriers to sustainability in the life sciences. We show how EOSC-Life provides a model for sustainable FAIR data management, including solutions for sensitive- and industry-related resources, by means of cross-disciplinary training and best practices sharing. Finally, we illustrate how data harmonisation and collaborative work facilitate interoperability of tools, data, solutions and lead to a better understanding of concepts, semantics and functionalities in the life sciences.




This research is mainly a product of the EOSC-Life European programme funding from the European Union's Horizon Europe research and innovation programme under grant agreement Nº824087. Complementary support was provided through EU funded project AgroServ (grant agreement Nº101058020), EU funded project BY-COVID (grant agreement Nº101046203), EU funded project DANUBIUS-IP (grant agreement Nº101079778), EU funded project EMPHASIS-GO (grant agreement Nº101079772), EU funded project FAIRplus (IMI grant agreement Nº802750), EU funded project FAIRsharing (Wellcome grant agreement Nº212930/Z/18/Z), EU funded project ISIDORe (grant agreement Nº101046133), EU funded project Precision Toxicology (grant agreement Nº965406), UKRI DASH (grant agreement NºMR/V038966/1). Special thanks to T. Biro and her radical collaboration team from Research Data Alliance who gave us great inspiration on how to lead this radical collaboration work.


PreprintZenodo_EMBOJ_Sustainability of FAIR Life Science Resources_V6_3_12092023WithFigures.pdf

Additional details


AgroServ – Integrated SERvices supporting a sustainable AGROecological transition 101058020
European Commission
EOSC-Life – Providing an open collaborative space for digital biology in Europe 824087
European Commission
FAIRplus – FAIRplus 802750
European Commission
ISIDORe – Integrated Services for Infectious Disease Outbreak Research 101046133
European Commission
DANUBIUS IP – DANUBIUS Implementation Phase Project - DANUBIUS-IP 101079778
European Commission
PrecisionTox – Toward Precision Toxicology: New Approach Methodologies for Chemical Safety 965406
European Commission
EMPHASIS-GO – Bringing EMPHASIS to operation: European Infrastructure for multi-scale Plant Phenomics and Simulation for food security in a changing climate 101079772
European Commission
BY-COVID – Beyond COVID 101046203
European Commission