(PART 1) Fat-free noncontrast whole-heart CMR with fast and power-optimized off-resonant water excitation pulses

(PART 1)

A novel short (1.0ms) binomial off-resonant RF excitation pulse for water excitation with reduced RF power deposit (LIBOR) was developed and tested in volunteers at 3T. A comprehensive comparison with previously published binomial off-resonant pulses BORR and LIBRE is provided. 

This repository contains raw imaging data and anonymized DICOM files (.dcm) of human volunteer experiments performed on a 3T clinical MRI scanner (MAGNETOM Prismafit, Siemens Healthcare, Erlangen, Germany) after written and informed consent was obtained from all participants. In this study, n=3 knee and n=10 cardiac datasets were collected and analysed. In each volunteer, the fat suppression properties of four pulses were studied: LIBOR (1.ms), BORR (1.0ms), LIBRE (1.0ms) and LIBRE (2.2ms).  All data was approved for collection and anonymized sharing under regulations from a local Ethics Committee (authorization CER-VD 2021-00708, Lausanne, Switzerland). 

*********************************************************************************************************************************

*********************************************************************************************************************************

Please cite the following work when using data from this repository:

Fat-free noncontrast whole-heart CMR with fast and power-optimized off-resonant water excitation pulses

A.L.C Mackowiak, D. Piccini, R. B. van Heeswijk, R. Hullin, C. Gräni, J.A.M. Bastiaansen (2024)

Link to publication: https://doi.org/10.1016/j.jocmr.2024.101096

*********************************************************************************************************************************

*********************************************************************************************************************************

Matlab code for simulation of the LIBOR, BORR and LIBRE RF pulses, as well as for reading and displaying the anyonymized raw data is available on GitHub at:
https://github.com/QIS-MRI/LIBOR_LIBRE_BORR_SimulationCode