BOLD & Non-BOLD Contrasts in Human fMRI
Description
This lecture was given as a part of the Weekend Educational Course on 'Advances in fMRI' at the 2023 Meeting of the International Society for Magnetic Resonance in Medicine. The video lecture is restricted to the attendees of the 2023 Meeting of the International Society for Magnetic Resonance in Medicine.
Talk Synopsis:
fMRI is a non-invasive method that allows scientists to study brain function during tasks or at rest. The BOLD contrast is the workhorse of functional neuroimaging. A cascade of physiological events following neuronal activity (changes in blood oxygenation, flow, and volume) culminates in the BOLD signal. The versatility of MRI enables imaging of blood flow and volume using techniques such as Arterial Spin Labeling (ASL) and Vascular Space Occupancy (VASO) respectively. In this talk, we will learn about BOLD and non-BOLD contrasts (CBF, CBV), discuss what they offer, and how they differ in their application to human fMRI.
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