The levels of inhibin A and inhibin B in PCOS patients

Background: Polycystic ovary syndrome (PCOS) is one of the main factors leading to infertility and ovulatory dysfunction in women. The aim of the current research is to study the levels of Inhibin A and Inhibin B in women with PCOS, depending on the level of Anti-millerian hormone.

Materials and methods: 30 infertile women (I group) with PCOS (excluding hyperprolactenemia, hypothyreosis, autoimmune thyroiditis) and 30 healthy women (II group) were involved in the study. Hormone profile in blood were determined on the 3rd day of menstruation with ELISA immunoferment analyzer. Results. It was determined an increase in Anti-Müllerian Hormone (AMH) secretion in PCOS patients with hyperandrogenia. Inhibin A and Inhibin B were lower in I group patients.

Conclusion. The detection of Inhibin A and Inhibin B in women with PCOS depending on the level of AMH plays the important role in the evaluation of ovarial reserve in infertile women with hyperandrogenemia.