Published July 31, 2022
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Fig. 8. Key 2D in Kiiacylphnols A H, eight undescribed polycyclic polyprenylated acylphloroglucinols with anticancer activities from Hypericum przewalskii Maxim
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- 1. H and C NMR calculations with DP4+ analyses, electronic circular dichroism (ECD) comparisons and calculations. Kiiacylphnols A and B were the first [3.3.1]-type PPAPs with an unusual octahydrooxireno[2,3-i]chromene scaffold bearing a rare 6/6/6/3 ring system. More significantly, kiiacylphnol A and oxepahyperforin displayed cytotoxicity against acute myeloid leukemia and diffuse large B-cell lymphoma cell lines by inducing cell apoptosis.
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Fig. 8. Key 2D correlations of compounds 7 and 8.
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Published as part of Duan, Yulin, Hu, Ping, Guo, Yi, Bu, Pengfei, Shi, Zhengyi, Cao, Yunfang, Zhang, Yeting, Hu, Hong, Tong, Qingyi, Qi, Changxing & Zhang, Yonghui, 2022, Kiiacylphnols A H, eight undescribed polycyclic polyprenylated acylphloroglucinols with anticancer activities from Hypericum przewalskii Maxim, pp. 1-11 in Phytochemistry (113166) 199 on page 8, DOI: 10.1016/j.phytochem.2022.113166, http://zenodo.org/record/8235738
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- Journal article: 10.1016/j.phytochem.2022.113166 (DOI)
- Journal article: urn:lsid:plazi.org:pub:56138D2E9433A57BFFA6FFC7A758FF87 (LSID)
- Journal article: https://zenodo.org/record/8235738 (URL)