The circadian clock of the bacterium B. subtilis evokes properties of complex, multicellular circadian systems
Creators
- 1. Ludwig-Maximilians-Universität München
- 2. Technical University of Denmark
- 3. Ludwig Maximilian University of Munich
- 4. John Innes Centre
Description
Circadian clocks are pervasive throughout nature, yet only recently has this adaptive regulatory program been described in non-photosynthetic bacteria. Here, we describe an inherent complexity in the Bacillus subtilis circadian clock. We find that B. subtilis entrains to blue and red light and that circadian entrainment is separable from masking through fluence titration and frequency demultiplication protocols. We identify circadian rhythmicity in constant light, consistent with Aschoff's Rule, and entrainment aftereffects, both of which are properties described for eukaryotic circadian clocks. We report that circadian rhythms occur in wild isolates of this prokaryote, thus establishing them as a general property of this species, and that its circadian system responds to the environment in a complex fashion that is consistent with multicellular eukaryotic circadian systems.
Notes
Data uploaded are in XLSX format.
Funding provided by: Volkswagen Foundation
Crossref Funder Registry ID: http://dx.doi.org/10.13039/501100001663
Award Number:
Funding provided by: Biotechnology and Biological Sciences Research Council
Crossref Funder Registry ID: http://dx.doi.org/10.13039/501100000268
Award Number: BB/P013511/1
Funding provided by: BRIC
Crossref Funder Registry ID: http://dx.doi.org/10.13039/501100002754
Award Number: BB/X01102X/1
Funding provided by: Deutsche Forschungsgemeinschaft
Crossref Funder Registry ID: http://dx.doi.org/10.13039/501100001659
Award Number: 507872050
Funding provided by: Chinese Scholarship Council Fellowship*
Crossref Funder Registry ID:
Award Number:
Funding provided by: Friedrich-Baur-Stiftung
Crossref Funder Registry ID: http://dx.doi.org/10.13039/501100008426
Award Number:
Funding provided by: Ludwig-Maximilians-Universität München
Crossref Funder Registry ID: http://dx.doi.org/10.13039/501100005722
Award Number:
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