Published July 30, 2023
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A primary hepatic lymphoma in a patient with Crohn's Disease receiving thiopurine and anti-TNF therapy: a case report.
Creators
- 1. university of medicine of Tunis
- 2. University of medicine of Tunis
Description
Primary Hepatic Lymphoma is a rare variant of non-Hodgkin's lymphoma with an incidence of 0.016% of all non-Hodgkin lymphomas. The most common histologic subtype is large diffuse B-cell lymphoma. Pathogenesis is not clearly established and undergoing immunosuppressive therapy has been proposed as a risk factor for primary hepatic lymphoma.
We report an intriguing case study, featuring a 23-year-old male patient with Crohn's Disease who had been receiving a combination therapy of thiopurine and anti-TNF for six years and was diagnosed with primary hepatic diffuse large B-cell lymphoma.
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