Published September 6, 2024 | Version 2.1.0
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Data for DeepRank2 tutorials

  • 1. Netherlands eScience Center

Description

This data contains raw PDB files and other metadata that can be used to run DeepRank2 tutorials for processing and later training on protein-protein interfaces and protein structures containing single residue variants.

The PDB files in data_raw/ppi/ folder have been generated using PANDORA software.

The PDB files in data_raw/srv/ folder have been retrieved from Ramakrishnan et al.

 

Files

data_raw.zip

Files (4.5 GB)

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md5:34b2e1b5e22ef7a9b757b8227c8bab9b
4.5 GB Preview Download
md5:ad410fae6039b2a5b0063b6913177824
7.5 MB Preview Download

Additional details

References

  • Marzella DF, Parizi FM, van Tilborg D, Renaud N, Sybrandi D, Buzatu R, Rademaker DT, 't Hoen PAC, Xue LC. PANDORA: A Fast, Anchor-Restrained Modelling Protocol for Peptide: MHC Complexes. Front Immunol. 2022 May 10;13:878762. doi: 10.3389/fimmu.2022.878762. PMID: 35619705; PMCID: PMC9127323.
  • Ramakrishnan G, Baakman C, Heijl S, Vroling B, van Horck R, Hiraki J, Xue LC, Huynen MA. Understanding structure-guided variant effect predictions using 3D convolutional neural networks. Front Mol Biosci. 2023 Jul 5;10:1204157. doi: 10.3389/fmolb.2023.1204157. PMID: 37475887; PMCID: PMC10354367.