Published April 13, 2024
| Version v3
Dataset
Open
Validation of de novo designed water-soluble and transmembrane proteins by in silico folding and melting
Creators
- 1. Structural Biology Brussel, Vrije Universiteit Brussel, Brussels, Belgium.
- 2. John Harvard Distinguished Science Fellowship Program, Harvard University, Cambridge, MA, USA
Description
Here are all of the datasets generated and analysed during this study.
Here is a breakdown of their content:
- 8_stranded_transmembrane_barrels.zip - raw data from Alphafold (3 and 48 recycles), ESMFold and raptor predictions of the 8 stranded TMBs. A file with all the sequences is also given
- 12_stranded_transmembrane_barrels.zip - raw data from the Alphafold and ESMfold predictions of the 12 stranded TMBs. A file with all the sequences is also given
- water_soluble_barrels.zip - raw data from the Alphafold and ESMfold predictions of the water soluble beta barrels (designable and non-designable). A file with all the sequences is also given
- all design models.zip - original design models for water-soluble (designable and non-designable), 8-stranded and 12-stranded TMBs
- ESMfold_masking_exp.tar - this tar file contains all the ESMfold masking experiments performed to the water-soluble, 8 and 12-stranded transmembrane barrels. Inside there are zipped datasets for each masking experiment
-
ziped_raw_csv_files.zip - raw csv files with all the data necessary to analyse the figures
-
analysis_notebooks.zip - Jupyter notebooks used to analyse the output prediction data for all figures
Files
12_stranded_transmembrane_barrels_updated.zip
Files
(3.7 GB)
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md5:baceb6e0d3ab0a9150982158e26a148b
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