Published June 20, 2023 | Version v1
Poster Open

Synthetic and structural studies of ruthenium complexes as DNA major groove binders

  • 1. University of Reading
  • 2. Diamond Light Source
  • 3. Dublin City University


Our crystal structure provides the first crystallographic evidence that a ruthenium polypyridyl complex can bind in the DNA major groove.


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NATURE-ETN – Nucleic Acids for Future Gene Editing, Immunotherapy and Epigenetic Sequence Modification 861381
European Commission