Changes in Lacrimation in experimentally induced Corneal Ulcers in Rabbits, treated with Third Eyelid Flap, Hyaluronic Acid and Platelet-Rich Plasma products

A clinical study was conducted on the effect of the lacrimation in New Zealand White rabbits (Oryctolagus cuniculus) treated with 4 different therapies (Third Eyelid Flap, hyaluronic acid eye drops, platelet-rich plasma as a single subconjunctival injection and as a triple daily instillation). For the study, daily measurements of tear production were performed using the 1-min Schirmer Tear Test (STT-I). In all groups, increased STT-I values were observed until the 3rd day after ulceration. Hyaluronic acid and platelet-rich plasma decreased the STT-I values to the baseline by the end of the study, with the earliest results noticed with plasma drops. Observed STT-I values in third eyelid fixation by the study's end are higher compared to the untreated eyes in the Control group.