THE RELATIONSHIP BETWEEN WAIST CIRCUMFERENCE, BODY MASS INDEX AND CORONARY ARTERY DISEASE IN PATIENTS WITH METABOLIC SYNDROME

Objective: Nowadays, with increasing incidence, metabolic syndrome has become an important health problem, because of high morbidity and mortality related to a strong relationship with coronary artery disease. Body mass index and waist circumference are anthropometric measurements that are being used to define obesity; a component of the metabolic syndrome. In this study, we aimed to investigate the relationship between body mass index, waist circumference and coronary artery disease and also diabetes mellitus and dyslipidemia which are accepted as major coronary artery disease risk factors in patients with metabolic syndrome.

Design, Setting, Subjects: There were 316 metabolic syndrome patients. We registered patients’ age, sex, waist circumference, body mass index, fasting glucose, triglyceride, HDL, LDL levels, history of diabetes mellitus and coronary artery disease and also ECG findings. We analyzed these findings using four different metabolic syndrome diagnostic criteria that are published by: NCEP ATPIII (2001), IDF (2005), WHO (1999), and Society of Endocrinology and Metabolism in Turkey(2009).

Results: Coronary artery disease was found in 66 (%20, 8) of our patients. We analyzed the relationship between coronary artery disease and metabolic syndrome parameters. There was a positive correlation between coronary artery disease and patients’ age (p:0,033), body mass index (p:0,050), waist circumference(p:0,048), diabettes mellitus (p:0,023), fasting glucose levels (p:0,004) and LDL levels (p:0,019). In addition, we showed the positive correlation between waist circumference, body mass index and diabetes mellitus; and a negative correlation between dyslipidemia.

Conclusions: We found a correlation between the two anthropometric indices and diabetes mellitus and dyslipidemia and also coronary artery disease directly and indirectly. In addition, the relationship between waist circumference and CAD was more powerful according to the relationship power. Also the relationship between waist circumference and coronary artery disease is much powerful according to the relationship power.