Published May 30, 2023 | Version v1
Dataset Open

Imaging data from "Live-cell 3D single-molecule tracking reveals modulation of enhancer dynamics by NuRD"

Authors/Creators

  • 1. Wellcome-MRC Cambridge Stem Cell Institute
  • 2. Department of Applied Mathematics and Computational Biology, Ecole Normale Supérieure, France
  • 3. Department of Biochemistry, University of Cambridge
  • 4. Department of Applied Mathematics and Computational Biology, Ecole Normale Supérieure
  • 5. Yusuf Hamied Department of Chemistry, University of Cambridge
  • 6. Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre
  • 7. The European Molecular Biology Laboratory EMBL
  • 8. Centre for Genomic Regulation (CRG)
  • 9. Helmholtz Zentrum München
  • 10. School of Biochemistry, University of Bristol
  • 11. MRC Laboratory of Molecular Biology Cambridge

Description

3D 20ms, 3D 500ms and 2D dCas9 raw videos, localisation, tracking and trajectory analysis data

From 'Live-cell 3D single-molecule tracking reveals modulation of enhancer dynamics by NuRD" (2021). Biorxiv. https://doi.org/10.1101/2020.04.03.003178

Files

20ms_CHD4.zip

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Additional details

Related works

Is published in
Preprint: 10.1101/2020.04.03.003178 (DOI)

Funding

UK Research and Innovation
Understanding how the NuRD complex regulates ES cell differentiation using single molecule fluorescence imaging MR/M010082/1
Wellcome Trust
Understanding mammalian interphase genome structure in mouse ES cells 206291
European Commission
4DCELLFATE - Developing a global understanding of the PRC and NuRD complexes in stem cell differentiation, in health and disease 277899
UK Research and Innovation
Transcriptional control of cell fate decisions by chromatin remodelling proteins MR/R009759/1
UK Research and Innovation
Understanding how the NuRD complex assembles and functions in mouse embryonic stem cells (mESC's) MR/P019471/1

References