CINECA Universal FAIR Data Compliant Federated Biomarker Discovery Service D5.2

This deliverable (D.5.2) allows clinical researchers to access and reuse existing data from public omics databases, to integrate these data with their own data and to enable access to a suite of bioinformatics tools, via the Galaxy workflow platform, for advanced cancer biomarker discovery and for patient stratification.

This deliverable (D5.2) provides FAIR data access from GA4GH public genomics data resources (e.g. European Genome Archive (EGA) using the GA4GH htsget protocol directly into Galaxy. We developed an online tutorial to explain our workflow in detail, which is associated with the Galaxy Training Network (GTN). This study shows it is feasible to adopt end-to-end (i.e. data to results) scalable FAIR analysis of clinical data, and ultimately for any future analysis on data available at the EGA. Additionally we have developed a unified resource, Cancer Galaxy, as a landing page for Cancer related workflows and tools1 which includes tools implemented/developed by CINECA and other bioinformatics groups from the EU and worldwide.