Managing PMT/vPvM Substances in Consumer Products through Functional Substitution: a Case-Study for Cosmetics

This poster presents the results of study aiming at applying the functional substitution approach to identify alternatives to PMT/vPvM substances used in cosmetic products. We first identified the market share of PMT/vPvM containing cosmetic products. Based on their high occurrence, the substances Allura red (CAS 25956-17-6), Benzophenone-4 (CAS 4065-45-6) and Climbazole (CAS 38083-17-9) were selected as case-studies for assessment of their functionality, availability of safer alternatives and essentiality. Via the alternatives assessment procedure, which used experimental and in silico data and three different multicriteria decision analysis (MCDA) strategies, safer alternatives were identified for all case-study chemicals.