Oral cavity health and remedy options to stimulate epithelization of oral mucosa

BOITSANIUK, Svitlana, CHORNIY, Sofiia, MANASHCHUK, Nadia, CHORNIJ, Natalia, POHORETSKA, Khrystyna, PATSKAN, Lyudmula & LEVKIV, Mariana. Oral cavity health and remedy options to stimulate epithelization of oral mucosa. Journal of Education, Health and Sport. 2023;27(1):53-65. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2023.27.01.005

https://apcz.umk.pl/JEHS/article/view/43897

https://zenodo.org/record/7911731

 

 

 

 

 

The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of December 21, 2021. No. 32343.

Has a Journal's Unique Identifier: 201159. Scientific disciplines assigned: Physical Culture Sciences (Field of Medical sciences and health sciences); Health Sciences (Field of Medical Sciences and Health Sciences).

Punkty Ministerialne z 2019 - aktualny rok 40 punktów. Załącznik do komunikatu Ministra Edukacji i Nauki z dnia 21 grudnia 2021 r. Lp. 32343. Posiada Unikatowy Identyfikator Czasopisma: 201159.

Przypisane dyscypliny naukowe: Nauki o kulturze fizycznej (Dziedzina nauk medycznych i nauk o zdrowiu); Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu).

© The Authors 2023;

This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland

Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike.

(http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.

The authors declare that there is no conflict of interests regarding the publication of this paper.

Received: 04.03.2023. Revised: 20.04.2023. Accepted: 09.05.2023. Published: 09.05.2023.

 

 

 

 

 

ORAL CAVITY HEALTH AND REMEDY OPTIONS TO STIMULATE EPITHELIZATION OF ORAL MUCOSA

 

Boitsaniuk Svitlana, Chorniy Sofiia, Manashchuk Nadia, Chornij Natalia, Pohoretska Khrystyna, Patskan Lyudmula, Levkiv Mariana*

*levkiv@tdmu.edu.ua

Author for correspondence:

Levkiv Mariana: levkiv@tdmu.edu.ua

 

Boitsaniuk Svitlana, 0000-0001-7742-1346  A, E, F

Chorniy Sofiia, 0000-0003-2718-5191  B,C,E 

Manashchuk Nadia, 0000-0001-6898-1149  A, B, E 

Chornij Natalia, 0000-0001-8145-7931  A, B, D 

Pohoretska Khrystyna, 0000-0002-6505-6086  B,C,F

Patskan Lyudmula, 0000-0003-2584-5942  B,C,E

Levkiv Mariana 0000–0001–7327–051X  A, D, E

 

A – Work concept and design

B – Data collection and analysis

C – Responsibility for statistical analysis

D – Writing the article

E – Critical review

F – Final approval of the article.

 

Boitsaniuk Svitlana, PhD, associate professor, Department of Dental Therapy, Dean of Dentistry Faculty, I.Horbachevsky Ternopil National Medical University, Maidan Voli 1, 46000 Ternopil, Ukraine; boucanuk@tdmu.edu.ua. 0000-0001-7742-1346

Chorniy Sofiia  Student of I.Horbachevsky Ternopil National Medical University, Maidan Voli 1, 46000 Ternopil, Ukraine; chornij_sofvol@tdmu.edu.ua. 0000-0003-2718-5191

Manashchuk Nadia, PhD, associate professor, Department of Dental Therapy, Faculty of Dentistry, I.Horbachevsky Ternopil National Medical University, Maidan Voli 1, 46000 Ternopil, Ukraine; manashchukn@tdmu.edu.ua. 0000-0001-6898-1149

Chornij Natalia, PhD, associate professor, Department of Dental Therapy, Faculty of Dentistry, I.Horbachevsky Ternopil National Medical University, Maidan Voli 1, 46000 Ternopil, Ukraine; chornij@tdmu.edu.ua. 0000-0001-8145-7931

Pohoretska Khrystyna, PhD, associate professor, Department of Dental Therapy, Faculty of Dentistry, I.Horbachevsky Ternopil National Medical University, Maidan Voli 1, 46000 Ternopil, Ukraine; pogoretska@tdmu.edu.ua. 0000-0002-6505-6086

Patskan Lyudmula, PhD, associate professor, Department of Dental Therapy, Faculty of Dentistry, I.Horbachevsky Ternopil National Medical University, Maidan Voli 1, 46000 Ternopil, Ukraine; patskan@tdmu.edu.ua. 0000-0003-2584-5942

Levkiv Mariana, PhD, associate professor, Department of Dental Therapy, Faculty of Dentistry, I.Horbachevsky Ternopil National Medical University, Maidan Voli 1, 46000 Ternopil, Ukraine; levkiv@tdmu.edu.ua. 0000–0001–7327–051X

 

 

ABSTRACT

Oral mucosa is an inner lining of oral cavity, which maintains different functions including protection of epithelial integrity. Pathology of oral mucosa can develop in response to the action of pathogenic microorganisms, viruses, and various traumatic factors; it can be a result of systemic pathology of a patient as well. Pain and discomfort usually accompanies such conditions leading to decrease of patient wellbeing. The basis of the pharmacological regulation of the regeneration process is the stimulation of wound healing.

The aim is to summarize and discuss the spectrum of remedy options that are used to stimulate epithelization of oral mucosa. The overall goal of the paper is to provide full and comprehensive information for dentists and their patients about medicament variety, ways of theirs application and dosage.

Methods. Relevant literature from MEDLINE (PubMed), Google Scholar, and in open access journals which are published by Elsevier was selected using the following key words «oral mucosa», «epithelization», and «remedy» were used in various combinations by the year of 2023. In total there were found 48 papers. To the selected scientific papers we applied the inclusion and exclusion criteria to choose the relevant ones.

Results. A comprehensive study of the available information related to means and products for epitelization of oral mucosa was carried out. Different groups of drugs can be used to stimulate regeneration process. The choice is set on vitamins, steroid anabolic agents, nonsteroidal anabolic agents, biogenic stimulants, immunomodulatory drugs, non-specific regeneration stimulators of plant and animal origin.

Conclusions. A significant number of drugs for the treatment of inflammatory processes in the oral cavity are available nowadays on dental market. Numerous studies, both domestic and foreign, substantiates the effectiveness of their use in dentistry. Therefore, when choosing pharmacological drugs, preference is given to drugs with a complex effect, which locally affect various links of the pathogenetic mechanism of the occurrence of diseases and do not disturb human wellbeing.

KEYWORDS: topical retinoid, oral mucosa, epithelization, herbal remedy, oral cavity