Long-COVID, neurological and cardiovascular disorders

Saienko Oleksandr, Chemych Mykola, Svitailo Vladyslav. Long-COVID, neurological and cardiovascular disorders. Journal of Education, Health and Sport. 2023;13(3):381-393. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2023.13.03.048

https://apcz.umk.pl/JEHS/article/view/43431

https://zenodo.org/record/7802534

The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of December 1, 2021. No. 32343.

Has a Journal's Unique Identifier: 201159. Scientific disciplines assigned: Physical Culture Sciences (Field of Medical sciences and health sciences); Health Sciences (Field of Medical Sciences and Health Sciences).

Punkty Ministerialne z 2019 - aktualny rok 40 punktów. Załącznik do komunikatu Ministra Edukacji i Nauki z dnia 1 grudnia 2021 r. Lp. 32343. Posiada Unikatowy Identyfikator Czasopisma: 201159.

Przypisane dyscypliny naukowe:Nauki o kulturze fizycznej (Dziedzina nauk medycznych i nauk o zdrowiu); Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu).

 © The Authors 2023;

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provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.

The authors declare that there is no conflict of interests regarding the publication of this paper.

Received: 22.02.2023. Revised: 10.03.2023. Accepted: .31.03.2023.

UDC: 616.98:578.834]-036.21:[616.83+616.1]-07-085

Long-COVID, neurological and cardiovascular disorders

Oleksandr Saienko, Mykola Chemych, Vladyslav Svitailo

Sumy State University, Ukraine

Department of Infectious Diseases

Oleksandr Saienko, ORCID: 0000-0003-2328-6606, o.saienko@kinf.sumdu.edu.ua

Mykola Chemych, ORCID: 0000-0002-7085-5448, n.chemych@kinf.sumdu.edu.ua

Vladislav Svitailo, ORCID: 0000-0003-3011-1003, v.svitailo@med.sumdu.edu.ua

Abstract

Introduction. After the disease COVID-19 caused by the SARS-CoV-2 virus, many people recover completely, but others have symptoms that persist for weeks, months or even years after the illness, with the number of patients who are worried about the signs of Long-COVID constantly growing.

The aim. Study of the features of the epidemiological and clinical course, pathophysiological mechanisms of long-COVID development, based on the study and analysis  of modern scientific data and the establishment of causal relationships of damage to the nervous and cardiovascular systems.  

Materials and methods. The electronic databases Scopus, PubMed, Web of Science, using modern technologies (Obsidian), key terms and words related to Long COVID, distant neurological and cardio-vascular complications have been studied and analyzed.

Conclusions. "Long COVID" is conceptualized as a multiorgan disorder with a wide range of clinical signs that may indicate primarily damage to the nervous and cardiovascular systems. Central or peripheral nervous system lesions occur in more than one-third of patients. Cardiovascular complications, including stroke, are the predominant causes of death of people with "long COVID" (40 %). The most frequent neurological signs of "Long COVID" (>70 %) are fatigue, headache, sleep disorders, emotional disorders and sensorimotor disorders. The processes of neuroinflammatory and oxidative stress predominate in the spread of neurological consequences of "Long COVID".

Keywords: COVID-19; Long-COVID; clinical signs; nervous and cardiovascular systems; cognitive impairment; consequences; health; environment.