A review on Oxazines: Synthesis and Biological Potentials

Due to their wide range of pharmacological effects, oxazine derivatives are a prominent class of heterocycle molecules that have attracted a lot of synthetic research. By appropriately substituting nitrogen and oxygen for carbon and hydrogen atoms in benzene and its reduction products, oxazine, a heterocyclic molecule, can be synthesised. Oxazine derivatives have emerged as attractive synthetic intermediates in recent years, as well as having significant biological properties like sedative, analgesic, antipyretic, anticonvulsant, antitubercular, antitumor, antimalarial, and antibacterial effects. The progress of drug resistance is currently a major challenge, and in order to address it, it is necessary to synthesise new classes of chemicals. The aim of the article's is to evaluate the generalisation of the information gathered regarding the synthesis of oxazine derivatives and their activity. For researchers interested in oxazine derivatives, we anticipate that this endeavour will be of particular interest.