Ovarian cancer is detectable from peripheral blood using machine learning over T cell repertoires
Authors/Creators
- 1. The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel
Description
To see if TCR repertoire obtained from peripheral blood is associated with tumor status, we collected blood samples from 97 women with or without ovarian cancer and produced T cell receptor information. Using machine learning, we stratified, with high success rates, the two groups, thereby associating peripheral blood T cell repertoire with the existence of ovarian cancer tumors.
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