Published November 23, 2023 | Version v2
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Ovarian cancer is detectable from peripheral blood using machine learning over T cell repertoires

Authors/Creators

  • 1. The Mina & Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel
  • 2. Ariel University
  • 3. ROR icon Sheba Medical Center

Description

To see if TCR repertoire obtained from peripheral blood is associated with tumor status, we collected blood samples from 85 women with or without ovarian cancer and produced T cell receptor information. Using machine learning, we stratified, with high success rates, the two groups, thereby associating peripheral blood T cell repertoire with the existence of ovarian cancer tumors.

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