Published June 22, 2023 | Version 1.1.0
Dataset Open

Supporting data for "Dissecting the cellular architecture of neuroblastoma bone marrow metastasis using single-cell transcriptomics and epigenomics unravels the role of monocytes at the metastatic niche"

Creators

  • 1. St. Anna Children's Cancer Research Institute, Vienna, Austria
  • 2. Department of Biosciences and Medical Biology, University of Salzburg, Salzburg, Austria
  • 3. Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Vienna, Austria; and Joint Metabolomics Facility, University and Medical University of Vienna, Vienna, Austria
  • 4. Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Vienna, Austria
  • 5. Department of Dermatology, Medical University of Vienna, Vienna, Austria
  • 6. CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria; and Center for Medical Statistics, Informatics and Intelligent Systems, Institute of Artificial Intelligence, Medical University of Vienna, Vienna, Austria

Description

This data repository contains several datasets supplementing the paper “Dissecting the cellular architecture of neuroblastoma bone marrow metastasis using single-cell transcriptomics and epigenomics unravels the role of monocytes at the metastatic niche” by Fetahu, Esser-Skala, Dnyansagar et al. (2023).

  • HOMER_Results.zip: detailed results of the HOMER analysis
  • nblast_scopen_gene_activity_normalized_motifs_added.rds: Seurat object with scATAC-seq data
  • snp_array.tgz: SNP array data
  • R_data_generated.tgz: Files generated by the scRNA-seq analysis scripts in the GitHub repository associated with the publication.

Notes

This study was funded by the Vienna Science and Technology Fund (WWTF#LS18-111, to S.T.M., N.F., and R.L.), MAPMET (FWF#P35841-B, to S.T.M.) by the Austrian Science Fund and LIQUIDHOPE (FWF#I4162, to S.T.M.) by the Transcan-2/ERA-NET initiative, EPICODE (FWF#P35072 to I.S.F.) by the Austrian Science Fund grant, and the St. Anna Kinderkrebsforschung e.V.

Files

HOMER_Results.zip

Files (18.6 GB)

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md5:4554933cdbe0238ffba241d6b045b953
7.3 MB Preview Download
md5:3602b5e9979223691fdc7dfd676c7b72
5.1 GB Download
md5:e5f64a5b38cac16480c8eae5b372038e
12.3 GB Download
md5:270259e94e18365028252a0292280bb8
1.2 GB Download

Additional details

Related works

Is required by
Software: https://github.com/csbg/neuroblastoma (URL)