CLINICAL AND LABORATORY- DIAGNOSTIC INDICATORS BY DINT OF FLOW CYTOFLUOROMETRY AND THE FREQUENCY PREVALENCE OF ACUTE LEUKEMIA AMONG PATIENTS CHILDREN

The article presents the results of immunotyping (IFT) studies by dint of the flowing cytofluorimetry method and determined frequency the of elicitation of acute leukemia among sick children in the Kyrgyz Republic( Kirghizia). In the diagnosis of acute leukemia with by dint of flow cytofluorometry, it is necessary to evaluate the immunophenotypical characteristics of tumor (blast) cells and determine their directions of myeloid, B and T linear or rare variants of vaguely linearity. According to the results of our studies, in typing immunophenotyping by dint of flow cytofluorimetry in prevalence disease revealed acute lymphoblastic leukemia in 68% of cases, acute myeloid leukemia in 29% of cases and acute leukemia of unclear linearity in 3% of cases. It is noted that, to the frequency of prevalence of acute leukemia among sick children of residents of the Kyrgyz Republic((Kirghizia), elicitation the incidence of acute myeloid leukemia among child females in 38% of cases, among child males in 23% of cases, and acute lymphoblastic leukemia occurs among child females in 62% of cases and in child males in 77% of cases. However, with timely diagnosis of acute leukemia with the determination of the linearity variant and the selection of PCTs, and with the presence of an HLA-identical healthy donor, haploidentical, closely related hematopoietic stem cell transplantation (brother, sister, parent or placental blood), in particular in children, gives the best results.