Published February 9, 2023 | Version 1
Dataset Open

BK Channels activation by N-type Ca2+ channels in the dendrites of neocortical pyramidal neurons

  • 1. LIPhy, CNRS UMR 5588

Description

This dataset contains imaging and whole-cell electrophysiological recordings from neocortical layer-5 pyramidal neuron dendrites in brain slices of the mouse.

Somatic electrophysiological and dendritic imaging recordings were done at 20 kHz. Imaging recordings were done with ~2.5 µm nm pixel resolution. These correspond to:

  • Voltage imaging (Figures 1 and 7)
  • Calcium imaging (Figures 2,3 and 4).

This dataset is used in the paper:

Blömer LA, Giacalone E, Abbas F, Filipis L, Migliore M, Canepari M. Kinetics and functional consequences of BK Channels activation by N-type Ca2+ channels in the dendrite of mouse neocortical layer-5 pyramidal neurons. bioRxiv, 2023 (https://www.biorxiv.org/content/10.1101/2023.10.26.564136v1).

Files

Files (685.8 kB)

Name Size Download all
md5:59c3632597239804c97fbb155b76236a
52.4 kB Download
md5:d4a87e6e11db2eda05067d729a17753b
23.5 kB Download
md5:69925a2dbf3124789feae7a46198949d
32.5 kB Download
md5:97d5cf46a8175e1f7f91484100af6efd
50.2 kB Download
md5:a45fef8cf8c5464e804f0d914378ff89
37.2 kB Download
md5:74d771eb953050e0822aceb42ac7e142
32.2 kB Download
md5:c4ac015a9c8f5979f342d961fd2282bf
46.0 kB Download
md5:af905e2ce1ceee8b7b179f2fc9fe0feb
32.1 kB Download
md5:bf3b63bae7e8b1cb515753174ef05d26
59.7 kB Download
md5:16f43bb4869499ba95cd73aab90a404a
43.2 kB Download
md5:d7d6cd1a67e4aa9600d4939c90c05d66
37.6 kB Download
md5:ede8ab6f0d8ce1868151671cf8442546
51.7 kB Download
md5:8914bb5a626549f1355ff32214109766
37.5 kB Download
md5:9956392e7d99f716d211aed294ecb527
36.4 kB Download
md5:7acf504f70dc78b16d9e02f6747a8d31
37.5 kB Download
md5:04386433230d3aeaf486d77b37d3ef66
38.0 kB Download
md5:92b8fe3e38e3481a9b6bea537832e18d
21.8 kB Download
md5:4c0e72719828e3515f65c55fb55c9b61
16.4 kB Download

Additional details

Funding

OptChemCom – Integrated optical, photochemical and computational technologies to study the physiological synergy of different ion channels ANR-18-CE19-0024
Agence Nationale de la Recherche
ICST – Canaux ioniques d'intérêt thérapeutique ANR-11-LABX-0015
Agence Nationale de la Recherche