Published January 21, 2023 | Version v1
Dataset Open

Data for "Deep Generative Priors for Biomolecular 3D Heterogeneous Reconstruction from Cryo-EM Projections" Part I

  • 1. ROR icon University of Toronto
  • 2. Hitachi High-Technologies Canada, Inc. based out of Victoria, BC

Description

Simulated datasets with uniformly distributed discrete states. Particle stacks, poses, CTFs and .star are available: (particle images downsampled to 256x256, original images 300x300x1.5A/pix available upon request)

  • One_rect: 49,973 particle images 
  • Two_circles: 49,761 particle images
  • Three_rect: 50,260 particle images

Results of aforementioned simulated datasets with:

  • Trained models (weights, latent encodings, config)
  • Reconstructed density maps for 121 discrete states (ground-truth .mrc/.pdb, LSGM-SPR result only due to space limit)
  • Analyze results (PCA-map, U-map, 10d z-alignment)

 

Related resources:

  • Original paper (Journal of Structural Biology): Deep Generative Priors for Biomolecular 3D Heterogeneous Reconstruction from Cryo-EM Projections
  • Github link: https://github.com/benjamin3344/DGP-SPR
  • Datasets part II: 10.5281/zenodo.10574539

Files

one_rectangle_256_50k_res4.5.zip

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