Published December 21, 2022 | Version 1

Purification of SLC12A5 from Expi293FTM Cells

  • 1. Centre for Medicines Discovery, University of Oxford. Oxford, UK

Description

This protocol is used to purify the SLC transporter expressed in Expi293FTM Cells using detergent solubilization followed by a series of different chromatographic methods. Depending on the nature of the expression construct and experimental requirements, the GFP tag can be removed using a proteolytic reaction.

Files

SP0017-6_SLC12A5 Purification.pdf

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Additional details

Funding

European Commission
ReSOLUTE - Research empowerment on solute carriers (ReSOLUTE) 777372