Published May 20, 2022 | Version v1
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Cytotoxicity Comparisons between "Young Protein" from Sea Star Igkappa Gene and Doxorubicine against Cancerous Mcf7 Cells

  • 1. Immunology of Invertebrates Orléans University, 556 rue Isabelle Romée, 45640 Sandillon (France)

Description

Some years ago, we found that Axial organ (AO) cells exerted an induced and spontaneous cytotoxicity against SP2 and MBL2 mouse tumoral cells. Recently, we discovered a sea star Igkappa gene with immune properties. This gene was first, inserted in a CMV (cytomegalovirus) and finally in a plasmid called « young » plasmid.
In the present experiment the sea star IGKappa gene was cloned in HeK human cells to produce the specific protein.
The induced« young » protein exerted a weak cytotoxicity against MCF7 cells.

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Peer review: 10.54289/JCVR2200106 (DOI)