MiXcan: a Framework for Cell-Type-Aware Transcriptome-Wide Association Studies with an Application to Breast Cancer

Song, Xiaoyu; Ji, Jiayi; Rothstein, Joseph H.; Alexeeff, Stacey E.; Sakoda, Lori C.; Sistig, Adriana; Achacoso, Ninah; Jorgenson, Eric; Whittemore,  Alice S.; Klein, Robert J; Habel, Laurel A.; Wang, Pei; Sieh, Weiva

doi:10.5281/zenodo.7350463

Published November 23, 2022 | Version v1.0

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MiXcan: a Framework for Cell-Type-Aware Transcriptome-Wide Association Studies with an Application to Breast Cancer

1. Icahn School of Medicine at Mount Sinai
2. Kaiser Permanente Northern California
3. Regeneron Pharmaceuticals
4. Stanford University School of Medicine

MiXcan is a statistical framework for performing cell-type-aware transcriptome-wide association studies with bulk profiling data. MiXcan R package is cataloged here.

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Created: November 23, 2022
Modified: November 23, 2022

MiXcan: a Framework for Cell-Type-Aware Transcriptome-Wide Association Studies with an Application to Breast Cancer

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