Published 2024
| Version v2
Dataset
Open
NanoString GeoMx DSP dataset from 12 primary/recurrent IDH-mutant astrocytoma samples
Creators
- 1. Department of Neurology, Brain Tumor Center at Erasmus MC Cancer Center; Laboratory of Tumor Immunology, Department of Medical Oncology
- 2. Department of Neurology, Brain Tumor Center at Erasmus MC Cancer Center
- 3. Department of Biostatistics, Erasmus MC University Medical Center, Rotterdam, The Netherlands
- 4. Laboratory of Tumor Immunology, Department of Medical Oncology
Description
NanoString GeoMx Digital Spatial Profiler data from 12 paired tumor resections of 6 IDH-mutant astrocytoma patients. All samples had an IDH-R132H mutation. all first resections were WHO 2016 grade II or III and second resections were WHO 2016 grade IV. The NanoString Cancer Transcriptome Atlas panel was used to measure RNA expression levels of ~1800 genes in 72 regions of interest. ROIs folder contains all images of the regions of interest used in this study, separated by tumor pairs. For information on methods see associated publication.