Linked Data Modeling Language (LinkML)
Published February 25, 2026 | Version v4.3.7
Software Open

Biolink Model: A universal schema for knowledge graphs in clinical, biomedical, and translational science

Authors/Creators

Description

What's Changed

  • Adding qualifier to ChemicalEntityToBiologicalProcessAssociation by @EvanDietzMorris in https://github.com/biolink/biolink-model/pull/1661
  • Test: linkml subproperty_of support for predicate constraints by @kevinschaper in https://github.com/biolink/biolink-model/pull/1670
  • refine evidence slot models by @RichardBruskiewich in https://github.com/biolink/biolink-model/pull/1668
  • Bump urllib3 from 2.5.0 to 2.6.3 by @dependabot[bot] in https://github.com/biolink/biolink-model/pull/1669
  • Add METPO prefix for microbial ecophysiological trait ontology by @Copilot in https://github.com/biolink/biolink-model/pull/1667
  • Change gene to disease or phenotypic association predicate by @RichardBruskiewich in https://github.com/biolink/biolink-model/pull/1673
  • Bump pymdown-extensions from 10.16 to 10.16.1 by @dependabot[bot] in https://github.com/biolink/biolink-model/pull/1665
  • Add diseases confidence score attribute by @mbrush in https://github.com/biolink/biolink-model/pull/1676
  • Adding text co-occurrence KL value in YAML by @mbrush in https://github.com/biolink/biolink-model/pull/1675
  • Bump pyasn1 from 0.6.1 to 0.6.2 by @dependabot[bot] in https://github.com/biolink/biolink-model/pull/1674
  • type constraint to qualified predicate slot by @RichardBruskiewich in https://github.com/biolink/biolink-model/pull/1682
  • add clinical approval status to association slot by @colleenXu in https://github.com/biolink/biolink-model/pull/1683
  • Add supporting_text slot to Association class by @kevinschaper in https://github.com/biolink/biolink-model/pull/1681
  • Add CHEMBL.TARGET as ID prefix for MacromolecularComplex by @vdancik in https://github.com/biolink/biolink-model/pull/1679
  • add evidence count to association by @sierra-moxon in https://github.com/biolink/biolink-model/pull/1677
  • predicate constraint changes on gene->phenotype|disease associations by @sierra-moxon in https://github.com/biolink/biolink-model/pull/1687
  • Clarify AnatomicalEntityToAnatomicalEntityPartOfAssociation semantics by @RichardBruskiewich in https://github.com/biolink/biolink-model/pull/1685
  • poetry-pyprojects-patch by @RichardBruskiewich in https://github.com/biolink/biolink-model/pull/1647
  • attributes.yaml: adjust diseases score to be float by @colleenXu in https://github.com/biolink/biolink-model/pull/1689
  • loosen predicate validation on chemical to BP association by @sierra-moxon in https://github.com/biolink/biolink-model/pull/1688
  • add temp diseases slot to association by @colleenXu in https://github.com/biolink/biolink-model/pull/1690
  • Refactor chemical/treatment association classes for treats vs adverse effects by @kevinschaper in https://github.com/biolink/biolink-model/pull/1691
  • tmkp confidence score is a float by @sierra-moxon in https://github.com/biolink/biolink-model/pull/1692
  • add slot to ChemicalEntityToDiseaseOrPhenotypicFeatureAssociation by @colleenXu in https://github.com/biolink/biolink-model/pull/1693
  • add temp G2P slot to attributes.yaml, GeneToDiseaseAssociation by @colleenXu in https://github.com/biolink/biolink-model/pull/1695
  • add Association for has_substrate data by @colleenXu in https://github.com/biolink/biolink-model/pull/1697
  • add descriptions, put routes of delivery on chemical entity by @sierra-moxon in https://github.com/biolink/biolink-model/pull/1701
  • Restructure affinity (parameter) slot model to facilitate annotation of the strength of chemical entity to gene or gene product interactions (e.g. in BindingDb data). by @RichardBruskiewich in https://github.com/biolink/biolink-model/pull/1703
  • binary relation by @RichardBruskiewich in https://github.com/biolink/biolink-model/pull/1704
  • Added pKon and pKoff; restructured enum, and added more descriptions by @RichardBruskiewich in https://github.com/biolink/biolink-model/pull/1705
  • additional ChEML and Drug-Rep. Hub attributes by @vdancik in https://github.com/biolink/biolink-model/pull/1702
  • prep for 4.3.7 release by @sierra-moxon in https://github.com/biolink/biolink-model/pull/1710

Full Changelog: https://github.com/biolink/biolink-model/compare/v4.3.6...v4.3.7

Notes

Please cite the following works when using this software.

Files

biolink/biolink-model-v4.3.7.zip

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Additional details

Related works

Is supplement to
Software: https://github.com/biolink/biolink-model/tree/v4.3.7 (URL)

Software

Repository URL
https://github.com/biolink/biolink-model